Cancer is a multifaceted disease that represents one of the leading causes of mortality in developed countries. Worldwide, one in eight deaths are due to cancer and it is the second most common cause of death in the US, exceeded only by heart disease. Studying characteristics of cancer patients and its economic impact on the patient is important as it enables us to understand the epidemiological status of the disease in the country and to monitor characteristics of disease management practices. This study aimed to explore the clinical and therapeutic characteristics of cancer patients in Iraq. Additionally, this study provided an estimate on the economic impact of cancer from patient perspective in Iraq. A total of 500 patients were involved in this study. A total of 15.2% of the patients had metastatic cancer. The most prevalent types of cancer were breast cancer (among females), ovarian cancer (among females) and lymphoma, with 53.9%, 10.5%, and 8.6%, respectively. The most commonly reported cancer therapy side effects among cancer patients. Nausea and vomiting, hair loss, and appetite loss were the most prevalent cancer therapy side effects with 85.2%, 75.2%, and 54.2%, respectively. The median total management cost is 2,765.0$ (IQR: 4,888.7$). There was a statistically significant difference in the median cancer management cost based on the stage of the disease, were stage two patients had a lower median cost compared to other patients (p<0.05). Type of cancer was another determinant that affected cancer management cost, were patients with stomach, colon, liver, and brain cancer statistically differed from others (p<0.05). Keywords: Cancer; Clinical; Cost; Iraq,