Background: Diabetes Mellitus (DM) poses a prevalent and costly health challenge worldwide, particularly in developing countries like Jordan, where non-adherence to treatment and self-care behaviors is a significant issue, highlighting the need to evaluate the impact of Short Massage System (SMS) in enhancing patient knowledge and awareness for improved disease management. Objective: To evaluate the effectiveness of short mobile reminder messages on improving adherence to self-care activities among patients with type 2 diabetes. Methods: A True-experimental study was conducted in three governmental Jordanian hospitals, including Al-Bashir Hospital, Princess Basma Hospital, and Prince Hamzah Hospital, with a total sample size of randomly selected 180 diabetic patients recruited from these settings. Participants were purposefully assigned to a control group (n=90) and an experimental group (n=90). The control group received usual care, while the experimental group received mobile reminder messages for a period of 3 months. Demographic variables included gender, age, occupation, educational level, and years since diagnosis. The primary outcome measure was adherence to self-care activities, assessed using "the Summary of Diabetes Self-Care Activities (SDSCA)" questionnaire. Pre-intervention and post-intervention scores had been in comparison between groups, and ANCOVA analysis was performed to control for demographic variables. Both descriptive statistics and inferential statistics (paired samples t-test, ANOVA, ANCOVA) were used to answer the research questions in this study. Results: No substantial disparities were found between the control and experimental groups in demographic variables at baseline. In the experimental group, "post-intervention SDSCA scores (M=35.2, SD=4.8) were significantly higher compared to pre-intervention scores (M=29.1, SD=5.1) with a mean difference of 6.1 (95% CI: 4.5-7.7, p<0.001) in all domains. In contrast, the control group showed no significant changes in SDSCA scores between pre-intervention (M=28.9, SD=4.9) and post-intervention (M=29.3, SD=5.2) measurements, with a mean difference of 0.4 (95% CI: -1.2-2.0, p=0.613)". ANCOVA analysis revealed a significant effect of the mobile reminder messages on improving adherence to self-care activities after controlling for demographic variables (F(1,177)= 36.71, p<0.001). Conclusion: Short mobile reminder messages proved to be successful in enhancing adherence to self-care activities among individuals diagnosed with type 2 diabetes. The incorporation of mobile reminder messages into diabetes self-management programs could be a valuable strategy to enhance self-care and promote better health outcomes in this population. Additional research is warranted to investigate the long-term effects and sustainability of such interventions. Keywords: Short Mobile Messages, T2DM, Self-care activities, Jordan.